The other day Salem itself was the recipient of several cracks on the show. First when Daniel and Carly were talking in the park Carly kept saying "Well it is Salem." in reference to all the crazy things happening.
Later Dr. Baker said "I hate this town" and then he said "It must be something in the water".
They are finally referencing how weird Salem is. How long before they find out about the the Salem tea and the Salem brain?